About

Providing straightforward information pertaining to drugs, drug use & drug policy. The Grey Pages promotes drug-related literacy and advocates a system of viable and tolerant drug policies. This is my personal collection of commentaries, essays, tid-bits, and other such writings on everything ranging from drug use, drug policy and drug-myths, to drug-science, addiction, human behavior, and the workings of the human brain. I started this blog with a particular focus on opioids, and over the past year have found my interest gravitate toward the intriguing, ever-changing world of designer intoxicants (i.e. "research chemicals" or "designer drugs").

Drug Portals (General)

Narcotics: i.e. Opioids, Opiates

Introduction to the Narcotic Drugs Summary of the world's most powerful euphoriant analgesics.

Morphine Family Portal Includes morphine and some of its immediate derivatives.

3,6 Morphine Esters Portal (Heroin Family) Includes heroin and more.

Codeine Family Portal (Codeines & Codones) Codeine, dihydrocodeine, hydrocodone, oxycodone, etc.

Hydrogenated Morphine Ketones Portal (Morphones) Hydromorphone, oxymorphone, etc.

Orvinols & Thevinols Portal (i.e. Bentley Compounds) Buprenorphine, etorphine, dihydroetorphine, etc.

Buprenorphine Portal An in depth overlook of buprenorphine.

Diphenyl Alkanes Portal (i.e. Open Chain Compounds) Methadone, dipipanone, dextromoramide, LAAM, etc.

Levorphanol Portal A powerful analgesic with a simplified morphine-like structure.

Phenylpiperidine Family Portal Meperidine, ketobemidone, etc.

Anilidopiperidine Family Portal (i.e. Fentanyl Compounds) Fentanyl, sufentanil, alfentanil, etc.

Atypical Opioids Portal (Tramadol, Tilidine, Etc) Tramadol, tilidine, tapentadol, etc.

More Background on the Bentley Compounds Fun facts about buprenorphine, etorphine, and more.



CNS Depressants:

Depressant Drugs: Overview A summary of the large family of central nervous system depressants, popularly known as "downers".

Benzodiazepine Portal This family includes widely used sedative hypnotics such as alprazolam (trade name Xanax), diazepam (trade name Valium), clonazepam (trade name Klonopin), lorazepam (trade name Ativan), and chlordiazepoxide (trade name Librium).

Nonbenzodiazepine Portal This family includes commonly prescribed sleep medications such as zolpidem (Ambien), zopiclone (Imovane), and eszopiclone (Lunesta).

Barbiturate Portal Barbiturates are a class of central nervous system depressants which include phenobarbital (Luminal), pentobarbital (Nembutal), amobarbital (Amytal), and secobarbital (Seconal).

Carisoprodol & Meprobamate Portal Two carbamate derivatives with mild sedative-hypnotic and muscle relaxant properties; known by the brand names Soma and Miltown, respectively.

GHB Portal A CNS depressant with sedative-hypnotic properties, known by the trade name Xyrem.

Alcohol Portal (i.e. Ethanol) The widely used central nervous system depressant.

Chloral Hydrate Portal A sedative-hypnotic drug and chemical reagent.

Cyclobenzaprine Portal A centrally acting muscle relaxant known by the trade name Flexiril.

Dissociatives:

What Are Dissociatives? A summary of the dissociative/dissociative-anaesthetic family of drugs.

DXM Portal The widely used cough suppressant and dissociative drug found in popular OTC medications such as Robitussin.

Ketamine Portal Also known as "Special K". It is a popular veterinary anaesthetic derived from arylcyclohexylamine, and is sometimes used in human procedures.

PCP Portal Also known as "Angel Dust" or simply "Dust". An arylcyclohexylamne derivative. It was once a veterinary anaesthetic but is now mostly available as a recreational drug.

Other Arylcyclohexylamines These include analogues of ketamine and PCP.

Nitrous Oxide Portal An oxide of nitrogen popularly known as "Laughing Gas". It is used in surgical procedures and is a mainstay of dental anaesthesia.

Ibogaine Portal A naturally occurring alkaloid derived from an exotic shrub known as iboga.

CNS Stimulants:

Amphetamine Family The popular family of stimulants which increase alertness, mood, and energy, and promote weight loss. Family includes the brand name drug Adderall, and its popular derivative, methamphetamine.

Substituted Amphetamines This family includes many uncommon analogues of amphetamine and methamphetamine, some of which are sold as research chems.

Aminopropylbenzofurans (i.e. Furan Substituted Amphetamines) A group of stimulant-entactogen drugs sometimes available as "research chemicals".

Aminoindane Family Another group of stimulant-entactogen drugs related to amphetamines and sometimes available as research chems.

Traditional Cathine/Cathinones Strong stimulants which occur naturally and are derived from the flowering "Khat" plant (pronounced as 'cot').

Substituted Cathinone Family This family consists of synthetic analogues of cathinone with stimulant properties. Substituted cathinones are sold in pure or diluted form, and traditionally appeared as the main ingredients in most of the "bath salt" products consumed as "legal highs".

Pyrovalerone Family (N-Pyrrolidinylcathinones) A specific sub-family of substituted cathinones, sold as research chemicals and novelty powders, and studied as potential stimulants for clinical use.

MDMA The enactogen-stimulant compound derived from methamphetamine. Commonly known as "Ecstasy" or "Molly".

Piperidine Family Piperidine derived stimulants often share fundamental similarities with amphetamine-type compounds, but their nitrogen atom is incorporated into a piperidine ring system.

Diphenylpyrrolidine Family These compounds share structural similarities with drugs of the piperidine family such as methylphenidate and desoxypipradol, as well as N-pyrrolidinyl-cathinones such as MDPV and a-PVP. 

Piperazine Family A class of stimulants derived from piperazine and at one point popular as research chemicals or recreational drugs.

Cocaine A tropane derived stimulant extracted from the leaves of the coca bush.

2C-X Family A family of phenethylamine derivatives with stimulant-enactogen and psychedelic properties.

Bupropion A substituted cathinone popularly used as an atypical antidepressant and smoking cessation agent, known by the trade name "Wellbutrin".

Modafinil A mildly stimulating wakefulness-promoting agent with an unusual structure, known by the trade name Provigil.

Atomoxetine A mild stimulant with an atypical structure, used clinically under the trade name Strattera.

Caffeine One of the most widely consumed legal intoxicants in the world, taken for its stimulating properties.

Overview of the MDxx Series (Ecstasy Analogues) A family of methylenedioxy substituted amphetamines and cathinones, with enactogen and stimulant properties. Often sold as research chemicals.

Psychedelics:

Tryptamines: Intro A brief overview of tryptamine derivatives, both naturally occurring and synthetically produced. Tryptamines serve as endogenous neurotransmitters/neuromodulators and as psychedelic-hallucinogenic drugs.

Tryptamines Portal Arguably the primary class of psychedelic drugs, most of which interact with the serotonergic pathways of the brain.

LSD Portal The research chemical turned psychedelic drug which influenced the counterculture of the 1960's and 1970's.

DOM Portal A substituted phenethylamine with psychedelic properties, known commonly as "STP" (for Serenity, Tranquility, Peace).

Mescaline Portal A naturally occurring substituted phenethylamine with psychedelic properties, traditionally derived from the Peyote Cactus.

Bromo-DragonFLY Portal A psychedelic substituted phenethylamine which has been used as a research chemical and recreational drug. Its atypical molecular structure resembles a dragonfly.

Ibogaine Portal A psychedelic/dissociative compound derived from the iboga plant. It has gained popularity  due to its ability reduce cravings for drugs such as opioids and cocaine (in dependent users).

Cannabis Portal The most widely consumed illicit substance in the world. It exhibits psychedelic and analgesic properties due to the presence of numerous alkaloids such as THC and cannabidiol, which target the endogenous cannabinoid system.

Hawaiian Baby Woodrose and LSA Portal A seed-bearing vine found in Hawaii and the Carribean and a natural source of the hallucinogenic LSD relative LSA.

Cannabinoids & Cannabinoid Receptors The cannabinoid family includes naturally occurring and synthetically produced compounds, of various structural families, which produce their effects via the endocannabinoid system.

Introduction to Psychedelics An overview of psychedelic drugs and their neurobiological properties.

An Overview of the Classic Psychedelics (i.e. Hallucinogens) A summary of psychedelic and hallucinogenic drugs, as they have traditionally been defined (interacting mainly with the serotonergic system of neurotransmission)

Research Chemicals (RC Products):

Research Chemicals (Overview) An overview of the large family of obscure psychoactives which are chemically analogous to many widely used drugs. They are often referred to as research chemicals due to their very limited history of clinical or mainstream use, and their appearances in scientific literature.

Substituted Amphetamines This family includes many uncommon analogues of amphetamine and methamphetamine, some of which are sold as "research chemicals".

Aminopropylbenzofurans A group of stimulant-enactogen drugs sometimes available as "research chemicals".

Pyrrolidine-Substituted Cathinones Portal (Pyrovalerones) A specific sub-family of substituted cathinones, sold as research chemicals and novelty powders, and studied as potential stimulants for clinical use.

Other Substituted Cathinones This family consists of synthetic analogues of cathinone with stimulant properties. Substituted cathinones are sold in pure or diluted form, and traditionally appeared as the main ingredients in most of the "bath salt" products consumed as "legal highs".

Aminoindanes Another group of stimulant-enactogen drugs related to amphetamines and sometimes available as "research chemicals".

Arylcyclohexylamines A group of dissociative compounds structurally related to ketamine and PCP.

Tryptamines: Intro A brief overview of tryptamine derivatives, both naturally occurring and synthetically produced. Tryptamines serve as endogenous neurotransmitters/neuromodulators and as psychedelic-hallucinogenic drugs.

Tryptamines Portal Arguably the primary class of psychedelic drugs, most of which interact with the serotonergic pathways of the brain.

Piperazines A class of stimulants derived from piperazine and at one point popular as research chemicals or recreational drugs.

Bromo-DragonFLY Portal A psychedelic substituted phenethylamine which has been used as a research chemical and recreational drug. Its atypical molecular structure resembles a dragonfly.

2C-X Family Portal A family of phenethylamine derivatives with stimulant-enactogen and psychedelic properties.

MDxx Series Portal A family of methylenedioxy substituted amphetamines and cathinones, with enactogen and stimulant properties. Often sold as research chemicals.

Benzodiazepine RC's Structural and functional analogues of popular sedative-hypnotics such as diazepam (Valium) and alprazolam (Xanax).

O-desmethyltramadol Portal An opioid analgesic which has not been used clinically, but has been available as a research chemical. It is a major metabolite of tramadol.

Fentanyl Analogues There seems to be a worrisome pattern emerging.

Atypical Opioids MT-45 and AH-7921.

Observations With 4-MEC, 4-FA, and 2-FMA (For Harm Reduction Purposes)

Other Drugs:

Kratom Portal (i.e. Mitragyna Speciosa) A tree native to Southeast Asia and related to the coffee bush, with leaves containing numerous opioid analgesics.

Salvia Portal A plant of the mint family with psychedelic properties when eaten or smoked, due to the presence of its active alkaloids.

Hawaiian Baby Woodrose Portal A seed-bearing vine found in Hawaii and elsewhere, and a natural source of the hallucinogenic LSD relative LSA.

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