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Providing straightforward information pertaining to drugs, drug use & drug policy. The Grey Pages promotes drug-related literacy and advocates a system of viable and tolerant drug policies. This is my personal collection of commentaries, essays, tid-bits, and other such writings on everything ranging from drug use, drug policy and drug-myths, to drug-science, addiction, human behavior, and the workings of the human brain. I started this blog with a particular focus on opioids, and over the past year have found my interest gravitate toward the intriguing, ever-changing world of designer intoxicants (i.e. "research chemicals" or "designer drugs").

Tuesday, June 4, 2013

Obscure Opioids Appearing as RC's

MT-45

Also known as IC-6.

MT-45 is a synthetic opioid analgesic discovered in the 1970's. Its mu agonist properties are evident although it may possess mixed agonist/antagonist properties similar to other compounds in its chemical class. It has a potency of roughly 3/4ths that of morphine. 

MT-45 is a N,N-di-substituted piperazine derivative. It structurally unrelated to most other opioids, with the exception of lefetamine, an atypical opioid with stimulant properties.

Little anecdotal information exists on the subjective effects of MT-45 (not to mention its toxicity profile or excretion patterns), however users have reported morphine-like effects ranging from mild to overbearing which last a few hours. Most users seem to administer MT-45 by the oral route.

AH-7921

Also known by the unofficial name Doxylam.

AH-7921 is a synthetic opioid selective for the morphine (micro, mu) receptor. It has a potency of roughly 3/4ths that of morphine. It is structurally unrelated to most other opioids and has not been used clinically, but has rarely appeared as recreational drug or research chemical.

Most users describe moderate analgesia with little euphoria. AH-7921 can be expected to have effects comparable to pentazocine, butorphanol, and other partial opioid agonists.

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