Providing straightforward information pertaining to drugs, drug use & drug policy. The Grey Pages promotes drug-related literacy and advocates a system of viable and tolerant drug policies. This is my personal collection of commentaries, essays, tid-bits, and other such writings on everything ranging from drug use, drug policy and drug-myths, to drug-science, addiction, human behavior, and the workings of the human brain. I started this blog with a particular focus on opioids, and over the past year have found my interest gravitate toward the intriguing, ever-changing world of designer intoxicants (i.e. "research chemicals" or "designer drugs").

Thursday, April 19, 2012

Ibogaine Vault

Ibogaine is a naturally occurring psychoactive compound found in the African “tabernanthe iboga” plant. Ibogaine is known for its potent psychedelic and dissociative properties. It has traditionally been used for entheogenic purposes, as part of a “coming of age ritual” (erowid), and has more recently become popular as a self-treatment for opioid addiction. Chemically, ibogaine is an atypical tryptamine derivative. Due to the presence of the tryptamine moiety (skeleton), it possesses serotonergic properties, acting as an 5HT2A agonist, thus producing some effects similar to LSD or psilocybin. In addition to serotonergic properties, ibogaine is an NMDA antagonist and a kappa receptor agonist - it is for this reason that the drug has proven useful in treating opioid dependence.

Further Reading (Off-Site): Ibogaine Experiences (Erowid)

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