Providing straightforward information pertaining to drugs, drug use & drug policy. The Grey Pages promotes drug-related literacy and advocates a system of viable and tolerant drug policies. This is my personal collection of commentaries, essays, tid-bits, and other such writings on everything ranging from drug use, drug policy and drug-myths, to drug-science, addiction, human behavior, and the workings of the human brain. I started this blog with a particular focus on opioids, and over the past year have found my interest gravitate toward the intriguing, ever-changing world of designer intoxicants (i.e. "research chemicals" or "designer drugs").

Sunday, March 25, 2012

Caffeine Vault

Caffeine is a popular psychostimulant that is chemically similar to the neurotransmitter adenosine. It is present throughout nature and occurs in chocolate and coffee beans. Caffeine is widely consumed for its mild psychostimulant effects. Its effects are produced by its binding and blocking (antagonizing) of the inhibitory adenosine receptor in the CNS, leading to an increase in excitatory neurotransmission. 

Caffeine is one of the most widely used and readily available psychoactives in the world and is consumed on a regular basis by a substantial portion of the population (for americans typically in the form of coffee or soda). Caffeine is known to produce physical dependence when regularly consumed, characterized by mild withdrawal symptoms upon discontinuation; millions of Americans are dependent on the drug in one form or another (although many moralists or "anti-drug" zealots might not be comfortable in acknowledging this, as it points out their mindless hypocrisy)

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