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Providing straightforward information pertaining to drugs, drug use & drug policy. The Grey Pages promotes drug-related literacy and advocates a system of viable and tolerant drug policies. This is my personal collection of commentaries, essays, tid-bits, and other such writings on everything ranging from drug use, drug policy and drug-myths, to drug-science, addiction, human behavior, and the workings of the human brain. I started this blog with a particular focus on opioids, and over the past year have found my interest gravitate toward the intriguing, ever-changing world of designer intoxicants (i.e. "research chemicals" or "designer drugs").

Sunday, March 18, 2012

O-desmethyltramadol

Known chemically as O-desmethyltramadol. M1 is an opioid analgesic originally known as the main active metabolite of the weak opioid tramadol. M1 has been marketed as a research chemical and is considerably more potent than tramadol as a mu agonist. It shows additional activity as a noradrenaline reuptake inhibitor, a 5HT2A antagonist and a muscarinic acetylcholine antagonist.

When sold as a research chemical, M1 typically appears in powder form, or as a mixture with certain herbal blends (kratom, etc).

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