About

Providing straightforward information pertaining to drugs, drug use & drug policy. The Grey Pages promotes drug-related literacy and advocates a system of viable and tolerant drug policies. This is my personal collection of commentaries, essays, tid-bits, and other such writings on everything ranging from drug use, drug policy and drug-myths, to drug-science, addiction, human behavior, and the workings of the human brain. I started this blog with a particular focus on opioids, and over the past year have found my interest gravitate toward the intriguing, ever-changing world of designer intoxicants (i.e. "research chemicals" or "designer drugs").

Saturday, July 30, 2011

Opioid Conversion & Equianalgesic Dosing

(search keywords: opioid dose conversion, equianalgesic dose, equivalency chart, relative potency, ratio, narcotic)

DISCLAIMER:

The numerous guides, both text and visual, are not intended to substitute for the advice of a qualified medical practitioner. The following  figures are presented for the purpose of informed use & harm reduction; knowledge  could very well save your life. Keep in mind that every individual's body will vary in how it responds to these drugs

Opioid Analgesics - Relative Potency 

Systemic/Parenteral (listed in morphine units)
Codeine 0.1 (~)
Pethidine 0.1
Hydrocodone 0.5
Oxycodone 0.6
Morphine 1
Heroin 2
Methadone 2
Levorphanol 5
Hydromorphone 5
Oxymorphone 7.5
Buprenorphine 33
Fentanyl 80 - 100 (~)

Oral (listed in morphine units)
Codeine 0.18 (~) or 1/6
Pethidine 0.18 (~) or 1/6
Morphine 1
Hydrocodone 1
Oxycodone 1.5
Heroin 1.5
Oxymorphone 3
Hydromorphone 3.78
Methadone 6 (~)
Levorphanol 7.5 (~)

Morphine Relative Potency Ratios (Oral and Parenteral)
Oxymorphone: PO 1 to 3 * IV 1 to 10
Hydromorphone: PO 1 to 5 * IV 1 to 6.6
Oxycodone: PO 1 to 1.5 * IV 1 to 0.66
Hydrocodone: PO 1 to 1 * IV 1 to 0.44
Methadone: PO 1 to 6 * IV 1 to 2.22
Levorphanol: PO 1 to 7.5 * IV 1 to 5
Buprenorphine: IV 1 to 30

Charts 

(for larger view, right click the image, select "open in new tab", click to zoom.)

Equianalgesic Dosing:


Transdermal Fentanyl Conversion:

Duragesic Transdermal - 
Per Patch Total Fentanyl Content:

12ug/h - 2.1mg
25ug/h - 4.2mg
50ug/h - 8.4mg
75ug/h - 12.6mg
100ug/h - 16.8mg

More:


See here for information on the relative potency of intranasal oxymorphone










1 comment:

  1. Stopping opiates is actually a difficult battle, nevertheless it could be gained using the proper resources. Today we are likely to assessment the top methods to relaxed withdrawal signs due to prolonged opiate habit in order to proceed to an existence located in restoration.
    loperamide for opiate withdrawal

    ReplyDelete