Providing straightforward information pertaining to drugs, drug use & drug policy. The Grey Pages promotes drug-related literacy and advocates a system of viable and tolerant drug policies. This is my personal collection of commentaries, essays, tid-bits, and other such writings on everything ranging from drug use, drug policy and drug-myths, to drug-science, addiction, human behavior, and the workings of the human brain. I started this blog with a particular focus on opioids, and over the past year have found my interest gravitate toward the intriguing, ever-changing world of designer intoxicants (i.e. "research chemicals" or "designer drugs").

Sunday, January 30, 2011

Nitrous Oxide Vault

(Also known as N2O, nitrous, or laughing gas)

N2O is a gaseous oxide of nitrogen. It has a variety of applications ranging from aerosol spray propellant, to rocketry or car engine oxidation agent. It is commonly used as a medical or dental anaesthetic and recreational drug. It is administered through inhalation.

Nitrous oxide is known to exhibit multiple actions on the central nervous system - first and foremost, it blocks the NMDA receptor. It also demonstrates anticholinergic activity (blocking the beta-2 nicotinic subtype). Also reported are its inhibion of AMPA, GABA-C, and 5HT3 receptors; and positive modulation of GABA-A receptors (i.e. BZD receptors).

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