The psychedelic class covers a large family and wide spectrum of psychoactive compounds which induce a spectrum of psychedelic effects ranging from trance-like meditative states, to hallucinations, dissociation, and temporary loss or distortion of self-awareness. For this reason, the term "psychedelic" is used in a very broad or generalized context. The psychedelic category consists of multiple specific drug classes, including but not limited to hallucinogens (LSD), deleriants (atropine), empathogens (MDMA), entheogens (peyote), or dissociatives (ketamine).
Empathogen-Enactogen: Empathy producing agent. Promotes emotional disinhibition, mood potentiation, and sociability. MDMA is the prototypic empathogen. Typically serotonergic and dopaminergic.
MDMA & MDPV
Hallucinogen: Produces profound canges and distortions in sensory perception, awareness, and thought process. LSD and psilocybin are classic hallucinogens. Typically serotonergic and in some cases, dopaminergic. (More on Classic Hallucinogens)
LSD & LSA
DMT, AMT, Bufotenin & 5-MeO-DMT
Sympathomimetic: Produces autonomic arousal (via exciting the sympathetic nervous system). Prototype stimulant effects. Typically dopaminergic and noradrenergic. The stimulant class is not itself a psychedelic class of drugs, however, many drugs of the psychedelic family (such as MDMA) are molecularly derived from stimulant compounds and produce some stimulant effects.
MDMA & MDPV
Dissociatives: Produces distortions in sensory perception. Inhibits the the conscious processing of sensory information, thus producing a bizzarre isolation of the mind from the body and environment. Often used as anaesthetics. Generally NMDA/glutametergic and dopaminergic.
Ketamine, Tiletamine & Methoxetamine
Deleriants: Produces symptoms mimicking a state of delerium or severe lack of sleep. Capable of producing actual hallucinogenic states; possibly consisting of encounters and conversations with persons who are not present. Primarily histaminergic and cholinergic.
Diphenhydramine & Dimenhydrinate
Atropine & Scopolamine
Nicotine (in high doses)
Entheogens: "From Within". Entheogenic compounds are classified based more on context of use than they are pharmacology. Often used for spiritual, religious, shamanic or self-exploratory purposes, for their transcendent and meditative properties. Psychedelic cacti and salvia divinorum have been used for these purposes. Many substances which are valued as entheogens are generally obtained and used in a raw or natural plant or extract state, this being especially true in the case of the "classic", traditional family of entheogens - the effects obviously being due to their active constituents.
Ayahuasca & Peyote (DMT)
Psychedelic Toads (Bufotenin & 5-MeO-DMT)
Magic Mushrooms (Psilocybin)
Salvia Divinorum (Salvinorin A)
Datura (Atropine & Scopolamine)